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Surfen dihydrochloride

CAS No. 5424-37-3

Surfen dihydrochloride( —— )

Catalog No. M34136 CAS No. 5424-37-3

Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Surfen dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity.
  • Description
    Surfen dihydrochloride is a potent HS (heparan sulfate) antagonist. Surfen binds to glycosaminoglycans. Surfen neutralizes the anticoagulant activity of both unfractionated and low molecular weight heparins. Surfen affects sulfation of heparin and inhibits degradation by heparin lyases. Surfen inhibits FGF2 binding and signaling. Surfen inhibits cell attachment, and virus infection.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Antibiotic | FGFR | Antiviral
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5424-37-3
  • Formula Weight
    445.35
  • Molecular Formula
    C21H22Cl2N6O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:? H2O : 8 mg/mL (17.96 mM)
  • SMILES
    Cl.Cl.Cc1cc(N)c2cc(NC(=O)Nc3ccc4nc(C)cc(N)c4c3)ccc2n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schuksz M, et al. Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13075-80.?
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